Smad1 and Smad8 Function Similarly in Mammalian Central Nervous System Development
نویسندگان
چکیده
منابع مشابه
The Role of Mammalian Target of Rapamycine Signaling Pathway in Central Nervous System Cancers: A Review
Mammalian mechanistic target of rapamycine (mTOR) is a conserved serine/threonine kinase in the cellular PI3K/Akt/mTOR signaling pathway. This pathway is modified by cellular alterations such as level of energy, growth factors, stresses, as well as the increased environmental level of cancerous cytokines. In general, increase of this kinase protein function is seen in various types of cancers, ...
متن کاملDevelopment-inspired reprogramming of the mammalian central nervous system.
In 2012, John Gurdon and Shinya Yamanaka shared the Nobel Prize for the demonstration that the identity of differentiated cells is not irreversibly determined but can be changed back to a pluripotent state under appropriate instructive signals. The principle that differentiated cells can revert to an embryonic state and even be converted directly from one cell type into another not only turns f...
متن کاملMicroglia Function in Central Nervous System Development and Plasticity.
The nervous system comprises a remarkably diverse and complex network of different cell types, which must communicate with one another with speed, reliability, and precision. Thus, the developmental patterning and maintenance of these cell populations and their connections with one another pose a rather formidable task. Emerging data implicate microglia, the resident myeloid-derived cells of th...
متن کاملADENOSINE IN THE CENTRAL NERVOUS SYSTEM
Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mecha...
متن کاملP124: Listeriosis in Central Nervous System
Listeriosis is one of the CNS inflammatory diseases which is happened majority in the form of sporadic. Listeriosis is ingested with the food. Infection occurrence in an exposed person depends on the number of organisms ingested, the virulence of the organisms strain and the individual condition. It is known that Listeriosis has decisive importance as an infection which the cellular immunodefen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2005
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.25.11.4683-4692.2005